Resource Type

Journal Article 181

Conference Videos 6

Conference Information 1

Year

2023 20

2022 16

2021 26

2020 5

2019 18

2018 13

2017 5

2016 14

2015 9

2014 8

2013 8

2012 13

2011 7

2010 7

2009 10

2008 1

2007 1

2000 2

open ︾

Keywords

cancer 27

lung cancer 16

breast cancer 8

cervical cancer 8

cancer therapy 7

Cancer 6

Colorectal cancer 5

targeted therapy 5

prostate cancer 4

Diagnosis 3

cancer immunotherapy 3

drug resistance 3

immunotherapy 3

Artificial intelligence 2

Breast cancer 2

COVID-19 2

DNA methylation 2

Exosomes 2

Glycosylation 2

open ︾

Search scope:

排序： Display mode:

Disabled homolog 2 is required for migration and invasion of prostate cancer cells

Yinyin Xie,Yuanliang Zhang,Lu Jiang,Mengmeng Zhang,Zhiwei Chen,Dan Liu,Qiuhua Huang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 312-321 doi: 10.1007/s11684-015-0401-3

Abstract:

Disabled homolog 2 (DAB2) is frequently deleted or epigenetically silenced in many human cancerIn this study, DAB2 expression was upregulated along with human prostate cancer (PCa

Keywords： DAB2     prostate cancer     migration     invasion     acetylation    

HTML PDF Collect

Human microbiome and prostate cancer development: current insights into the prevention and treatment

Solmaz Ohadian Moghadam, Seyed Ali Momeni

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 11-32 doi: 10.1007/s11684-019-0731-7

Abstract: The human microbiome may influence prostate cancer development.of the human microbiome in relation to prostate cancer risk.Current studies suggest that the microbiota of men with prostate cancer significantly differs from thatcancer.cancer.

Keywords： microbiome     prostate cancer     prevention     treatment     molecular pathological epidemiology (MPE)     biomarker    

HTML PDF Collect

Detection and monitoring prostate specific antigen using nanotechnology approaches to biosensing

Grant Perry, Fernando Cortezon-Tamarit, Sofia I. Pascu

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 1,   Pages 4-18 doi: 10.1007/s11705-019-1846-8

Abstract: Prostate cancer has a high incidence in men and remains the second cause of mortality due to cancer.The detection of the prostate specific antigen (PSA) in blood samples has been the preferred method forthe detection and monitoring of prostate cancer over the past decades.cancer and the detection of its different forms and incorporation in multiplexed designs with otherbiomarkers still remains a highly valuable indicator in the theranostics of prostate cancer.

Keywords： biosensing     immunosensor     PSA     prostate cancer     fluorescence    

HTML PDF Collect

Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and

Runlin Shi,Haibing Xiao,Tao Yang,Lei Chang,Yuanfeng Tian,Bolin Wu,Hua Xu

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 456-463 doi: 10.1007/s11684-014-0353-z

Abstract: can function as tumor suppressors or oncogenes that target many cancer-related genes.miR-200c) on the biological behavior and mechanism of proliferation, migration, and invasion in the prostatecancer cell line Du145.Results showed that DU145 cells exhibited a high expression of miR-200c compared with immortalized normal prostateHence, miR-200c could significantly inhibit the proliferation of the prostate cancer cell line Du145;

Keywords： miR-200c     proliferation     migration     invasion     prostate cancer     Du145 cell     ZEB1    

HTML PDF Collect

Neoadjuvant radiohormonal therapy for oligo-metastatic prostate cancer: safety and efficacy outcomes

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 231-239 doi: 10.1007/s11684-022-0939-9

Abstract: To evaluate the safety and efficacy of neoadjuvant radiohormonal therapy for oligometastatic prostatecancer (OMPC), we conducted a 3 + 3 dose escalation, prospective, phase I/II, single-arm clinical trialsecondary outcomes were radiological treatment response, positive surgical margin (pSM), postoperative prostate-specificIn all, neoadjuvant radiohormonal therapy is well tolerated for oligometastatic prostate cancer.

Keywords： neoadjuvant     radiotherapy     oligometastatic     prostate cancer     radical prostatectomy    

HTML PDF Collect

Ultrasound-guided prostate percutaneous intervention robot system and calibration by informative particle

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 1,   Pages 3-3 doi: 10.1007/s11465-021-0659-x

Abstract: Applying a robot system in ultrasound-guided percutaneous intervention is an effective approach for prostatecancer diagnosis and treatment.

Keywords： ultrasound image guidance     prostate percutaneous intervention     parallel robot     kinematics identification    

HTML PDF Collect

Human Prostate-Specific Antigen Carries N-Glycans with Ketodeoxynononic Acid Article

Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer

Engineering 2023, Volume 26, Issue 7,   Pages 119-131 doi: 10.1016/j.eng.2023.02.009

Abstract: associations have been found between elevated concentrations of free or conjugated Kdn in relation to human cancerHere, we report for the first time that Kdn is expressed on prostate-specific antigen (PSA) Nprostatecancer (PCa), although no differences were found between PCa and non-PCa patients.

Keywords： Ketodeoxynononic acid     Kdn     Glycosylation     Prostate cancer     Prostate-specific antigen    

HTML PDF Collect

NES1/KLK10 and hNIS gene therapy enhanced iodine-131 internal radiation in PC3 proliferation inhibition

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 646-657 doi: 10.1007/s11684-018-0643-y

Abstract: gene is thought to be a tumor-suppressor gene. Our previous study found that overexpression of gene in PC3 cell line could slow down the tumor proliferation rate, associated with a mild decrease in expression. The decrease could increase the sensitivity of radiotherapy to tumors. Thus, we supposed to have an “enhanced firepower” effect by combining overexpressed gene therapy and I radiation therapy uptake by overexpressed hNIS protein. We found a weak endogenous expression of hNIS protein in PC3 cells and demonstrated that the low expression of hNIS protein in PC3 cells might be the reason for the low iodine uptake. By overexpressing in PC3, the radioactive iodine uptake ability was significantly increased. Results of and tumor proliferation experiments and F-fluorothymidine ( F-FLT) micro-positron emission tomography/computed tomography (micro-PET/CT) imaging showed that the combined gene therapy and I radiation therapy mediated by overexpressed hNIS protein had the best tumor proliferative inhibition effect. Immunohistochemistry showed an obvious decrease of expression and the lowest expression. These data suggest that via inhibition of expression, overexpressed might enhance the effect of radiation therapy of I uptake in overexpressed PC3 cells.

Keywords： androgen-independent prostate cancer     normal epithelial cell-specific 1/kallikrein 10     sodium/iodide symporter    

HTML PDF Collect

Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 942-942 doi: 10.1007/s11684-021-0876-z

HTML PDF Collect

Progress and challenges in RET-targeted cancer therapy

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 207-219 doi: 10.1007/s11684-023-0985-y

Abstract: Oncogenic RET fusions or mutations are found most often in non-small cell lung cancer (NSCLC) and inthyroid cancer, but also increasingly in various types of cancers at low rates.

Keywords： pralsetinib     selpercatinib     RET-alteration     lung cancer     thyroid cancer     tumor-agnostic therapy     drug    

HTML PDF Collect

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 361-373 doi: 10.1007/s11684-018-0656-6

Abstract: termed the epithelial-to-mesenchymal transition (EMT) plays an important role in both development and cancerinvasiveness, drug-resistance and the ability to form metastases at distant organs, and thereby contribute to cancer

Keywords： epithelial-to-mesenchymal transition     cancer     metastasis     cancer stem cell    

HTML PDF Collect

Metformin for cancer prevention

Yonghua Yang

Frontiers of Medicine 2011, Volume 5, Issue 2,   Pages 115-117 doi: 10.1007/s11684-011-0112-3

HTML PDF Collect

Title Author Date Type Operation

Disabled homolog 2 is required for migration and invasion of prostate cancer cells

Yinyin Xie,Yuanliang Zhang,Lu Jiang,Mengmeng Zhang,Zhiwei Chen,Dan Liu,Qiuhua Huang

Journal Article

Human microbiome and prostate cancer development: current insights into the prevention and treatment

Solmaz Ohadian Moghadam, Seyed Ali Momeni

Journal Article

Detection and monitoring prostate specific antigen using nanotechnology approaches to biosensing

Grant Perry, Fernando Cortezon-Tamarit, Sofia I. Pascu

Journal Article

Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and

Runlin Shi,Haibing Xiao,Tao Yang,Lei Chang,Yuanfeng Tian,Bolin Wu,Hua Xu

Journal Article

Neoadjuvant radiohormonal therapy for oligo-metastatic prostate cancer: safety and efficacy outcomes

Journal Article

Luo Jun: Treatment Selection in Prostate Cancer（2019.8.16）

22 Apr 2021

Conference Videos

Ultrasound-guided prostate percutaneous intervention robot system and calibration by informative particle

Journal Article

Human Prostate-Specific Antigen Carries N-Glycans with Ketodeoxynononic Acid

Wei Wang, Tao Zhang, Jan Nouta, Peter A. van Veelen, Noortje de Haan, Theo M. de Reijke, Manfred Wuhrer, Guinevere S.M. Lageveen-Kammeijer

Journal Article

Huang Jiaoti: Amino Acid Metabolism in Therapeutic Failure and Disease Progression of Prostate Cancer

22 Apr 2021

Conference Videos

Zhang Qing: Proton Heavy Ion Therapy for Prostate Cancer（2019.8.17）

22 Apr 2021

Conference Videos

NES1/KLK10 and hNIS gene therapy enhanced iodine-131 internal radiation in PC3 proliferation inhibition

Jiajia Hu, Wenbin Shen, Qian Qu, Xiaochun Fei, Ying Miao, Xinyun Huang, Jiajun Liu, Yingli Wu, Biao Li

Journal Article

Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer

Journal Article

Progress and challenges in RET-targeted cancer therapy

Journal Article

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

Yun Zhang, Robert A. Weinberg

Journal Article

Metformin for cancer prevention

Yonghua Yang

Journal Article